Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells
نویسندگان
چکیده
منابع مشابه
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells
We explored the cytotoxic effects of nanobacteria (NB) and nanohydroxyapatites (nHAPs) against human choriocarcinoma cells (JAR) and the mechanisms of action underlying their cytotoxicity. JAR cells were co-cultured with NB and nHAPs for 48 h, and ultrastructural changes were more readily induced by NB than nHAPs. Autophagy in the plasma of JAR cells were observed in the NB group. The rate of a...
متن کاملCytotoxicity and apoptosis induced by nanobacteria in human breast cancer cells
BACKGROUND The existing evidence that nanobacteria (NB) are closely associated with human disease is overwhelming. However, their potential toxicity against cancer cells has not yet been reported. The objective of this study was to investigate the cytotoxic effects of NB and nanohydroxyapatites (nHAPs) against human breast cancer cells and to elucidate the mechanisms of action underlying their ...
متن کاملMorphological differentiation of human choriocarcinoma cells induced by methotrexate.
BeWo is a malignant human choniocarcinoma line derived from a methotmexate-nesistantumor. Under normal conditions, two BeWo phenotypes coexist in culture. The predominant form, 96 to 99% of the total population, consists of cytotro phoblast-like (CTL) cells that are proliferative, mononucleate, and moderate in size. The remaining cells are syncytiotropho blast-like (STL), being giant, nonprolif...
متن کاملLactobacillus Acidophilus Cytotoxicity Effect and Apoptosis in Human Bladder Carcinoma Cells: An In Vitro Study
Introduction: Anticancer effects of Lactobacillus acidophilus, as a probiotic bacterium, have been indicated in several studies. There are common therapeutic options for bladder cancer treatment; however, their side effects and recurrence of disease are considerable. Therefore, complementary medication is essential and it must be safe and effective. In the present research, we assessed the anti...
متن کاملInhibition of Methotrexate-induced Differentiation of Cultured Human Choriocarcinoma (BeWo) Cells by Thymidine1
During exposure to methotrexate, cultured human choriocarcinoma (BeWo) cells stop proliferating, enlarge, and undergo a complex differentiative response that resembles in utero development of quiescent syncytiotrophoblasts. In the present work, complete inhibition of prolif eration and maximal cell enlargement required exposure to 1 MMmeth otrexate, whereas colony-forming ability, determined af...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nanoscale Research Letters
سال: 2014
ISSN: 1556-276X
DOI: 10.1186/1556-276x-9-616